Safeguarding evidence-based decision making in the FDA for COVID-19 vaccines

The Feasibility of Evidence- based Decision Making in a Toxicology Emergency Case

Evidence- Based Medicine (EBM) aims to bring the best available evidence into clinical practice.  Different clinical methods of education such as in-patient rounds, follow up rounds, out-patients rounds, group sessions, grand rounds, lectures, and journal clubs could be held by EBM approach. The current text presents two interrelated case reports; a case report of EBM decision making in an emer...

Making evidence-based selections of influenza vaccines

Years ago, intramuscular influenza vaccines were the only option for those who wanted to arm themselves against the flu. Today there are alternatives, including intradermal injections and intranasal sprays. In order to select the right influenza vaccine for their patients, pharmacists, and other healthcare professionals must have a basic understanding of the immune system. Influenza vaccines el...

The Use of Evidence by Decision-Making Committees

Vitamin D discovery outpaces FDA decision-making

The US FDA currently encourages the addition of Vitamin D to milk and cereals, with the aim of reducing rickets in children, and osteoporosis in adults. However, Vitamin D not only regulates the expression of genes associated with calcium homeostasis, but also genes associated with cancers, autoimmune disease, and infection. It does this by controlling the activation of the Vitamin D Receptor (...

Prioritization of COVID-19 Patients for Admission in the Intensive Care Unit in the Context of Hospital Bed Shortages: An Integrated Multi-criteria Decision Making Approach

Background: When an epidemic occurs, resources, including hospital beds, are severely limited and not all patients can be treated; so, hospital bed rationing is inevitable. Therefore, the aim of this study is to provide a method for evaluating and prioritizing patients with COVID-19 for admission to the intensive care unit. Methods: This was a descriptive-survey study in terms of data collecti...